Month: November 2014

Can An Ebola Vaccine Be Developed in Time

According to a recent article published in Frontiers of Immunology, “Ebola (as with all infectious pathogens) has evolved to circumvent innate immunity by appropriating anti-viral pathways and suppressing a viable immune system response”. Ebola’s superior resistance to immunological strategies coupled with its ability to generate incredibly high levels of cytokines and other inflammatory chemicals in the body is what makes Ebola so lethal. However, researchers are hoping to garner clues from people who survive Ebola infections regarding properties of antibodies that could be used to develop a viable vaccine. What We Know about Ebola • African fruit bats are probably potential reservoirs of the Ebola virus. • In non-fatal cases of Ebola , patients typically show improvement between day six and day 11 following onset of symptoms while simultaneously presenting a lymphatic fluid and plasma antibody response. • Five species of the Ebola virus are known to exist: Sudan, Zaire, Reston, Bundibugyo and the Côte d’Ivoire. • The first known Ebola outbreak occurred in the 1970s in Sudan and the Democratic Republic of the Congo. No additional cases of Ebola were subsequently confirmed in Africa until 1994. • Glycoprotein spikes embedded in the virus bind to human cells and promote fusion between host cell membranes and the viral envelope. This action enables the Ebola virus to enter host cell cytoplasm, infect the cell and generate an inflammatory response from...

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ADHD and Substance Abuse as Co-Occurring Disorders

While the term Attention Deficit Hyperactivity Disorder (ADHD) continues to be thrown around to describe a misbehaved or hyperactive individual, it becomes increasingly more important that we dispel myths about the disorder. As defined by the Diagnostic and Statistical Manual of Mental Health (DSM-5) and published in the American Psychiatric Association (APA), symptoms of ADHD include: Inability to remain on task Difficulty organizing tasks/activities Inability to meet deadlines Unwillingness to engage in activities that require focusing Easily distracted Excessive and fast paced talking Always “on the go” Consistently interrupting others Consistent daydreaming Despite common belief, ADHD is not a behavior malfunction, rather, it is a serious disorder. Typically, those who suffer from ADHD often experience troubles with substance abuse as well. The co-occurring disorders become far more difficult to diagnose and treat, often resulting in mistreatment or neglect. The American Academy of Family Physicians has concluded that 30-50% of individuals who are diagnosed with ADHD continue to experience symptoms throughout their adult lives. Of those suffering from ADHD, nearly half of them experience some form of substance abuse disorder. Why is there a connection between ADHD and substance abuse disorder? Those who experience symptoms from ADHD are looking for a way to calm down. Drugs and alcohol often have temporary calming effects that allow ADHD patients to focus and relax. Those who have difficulty focusing or relaxing during social...

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RSS Addiction News

  • Polysubstance Abuse: Addicted to the ‘High’ Rather Than the Drugs February 21, 2018
    Until there’s a social consensus, it bears repeating that addiction is a complex and complicated disease of the brain. People develop the condition for a variety of different reasons, which makes plotting out an effective treatment approach a challenge for patients, physicians, therapists and other addiction healthcare specialists. That said, the treatment of addiction continues […]
  • Driving Under the Influence Just Got a Lot Weirder February 14, 2018
    In all 50 states, the legal blood alcohol limit (BAC) for anyone operating a motor vehicle is .08, though advocates continue pressuring legislators to bring it down to a .05 BAC. Public awareness campaigns, new laws and stricter penalties regarding DUI violators were launched in the mid 1970s. The original campaigns highlighted the gruesome realities […]
  • Hygge [hew-guh] to Beat the Winter Blues and Improve Mental Health: The Danes Know What They’re Doing February 7, 2018
    As the grip of post-holiday wintertime clamps down on North America, it’s all too common to allow the shorter days, frigid temperatures and stress of getting back to work push us into isolation, both physically and mentally. In Denmark, where the average temperature in January is about 28 degrees Fahrenheit and 0 degrees in February, […]

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